Lung Cytology & FISH

Equivocal respiratory cytology can be a diagnostic challenge and may make it impossible to yield a firm diagnosis by analyzing cytomorphology alone. We have prepared an online gallery of 30 respiratory cytologies including „atypical“ sepcimens as well as some positive and negative controls. Each of the shown cell groups have been analyzed by multi-target FISH (LA Vysion) after PAP image capturing and automatic relocalization. Positive FISH results were restricted to carcinoma patients and conversely all benign cases had a negative FISH result. The diagnoses had been confirmed by clinical follow up and/or biopsy. You may take the test and then view the solutions and the percentage of answers given by the 137 expert participants.

This webpage is part of Pathorama.

© Institut für Pathologie Basel / Prof. Dr. med. Lukas Bubendorf & PD Dr. med. Katharina Glatz-Krieger

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